today EAO Lisbon 27 September 2019
Nobel Biocare brings latest innovations to Lisbon / President of Portugal welcomes attendees at EAO 2019 / News / Floor plan / List of exhibitors / Industry / Travel
Nobel Biocare brings latest innovations to Lisbon / President of Portugal welcomes attendees at EAO 2019 / News / Floor plan / List of exhibitors / Industry / Travel
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DTI spoke with Prof. Jocelyne Feine from McGill University about the challenges of implant procedures in older people. The 2019 EAO congress offers an opportunity to see and try out the most current innovations in implant dentistry. » page 2 » page 4 » page 10 Nobel Biocare brings latest innovations to Lisbon The Mucointegration concept, edentulism and a new implant system in focus at EAO. This year, Nobel Biocare opened a new chapter for implant dentistry with the launch of new surfaces and the introduction of the new Nobel Biocare N1 implant system. Visitors to the EAO have the opportunity on Friday, 27 September, to view these groundbreaking innovations and discover more about them during an engaging symposium and through interactive hands-on sessions. Sharing their expertise at the industry symposium will be Dr Tristan Staas and Prof. Gabor Tepper, two of the leading implant clinicians in Europe. They will provide exclusive insights into how Nobel Biocare N1 is set up to revolutionise patient care. In order to address some of the shortcomings of current protocols, the recently introduced system was designed from the ground up according to biological principles and keeping patient needs in mind. Going beyond this new implant design, Nobel Biocare N1 is also redefining site preparation with the introduction of the OsseoShaper, an innovative alternative to conventional drilling protocols. Experiences from over 24 months of clinical evaluations of the Nobel Biocare N1 concept with an early ambassador group have already indicated promising results in terms of the method’s effectiveness. Embodying the Mucointegration concept, Nobel Biocare’s Xeal and During the symposium, Staas and Tepper will be joined by the worldrenowned clinician Dr Paulo Maló from Portugal, who will demonstrate how the NobelPro Line helps clinicians to master even the most challenging cases and treat more edentulous patients. The Nobel Biocaresponsored symposium will take place on 27 September from 17:15 to 19:15 in the main auditorium of the Lisbon Congress Centre. Attendance is free with registration for the congress, and visitors are invited to come early to secure their seats. Attendees interested in developing their practices further can take part in two hands-on sessions held by Nobel Biocare on Friday. In addition to a morning session on immediate restorations led by Staas, Tepper will demonstrate in the afternoon how to achieve optimal primary stability for immediate restorations in all bone densities through different drill protocols. Those who wish to attend the workshops are invited to visit the Nobel Biocare booth at EAO 2019 to find out whether seats are still available. © DTI Well-attended Nobel Biocare booth on the first congress day. TiUltra surfaces will be available on the Nobel Biocare N1 implant system from the start. With the help of their specially tailored surface chemistry and topography, the sys- tem’s implants and abutments will benefit from optimised tissue integration. These new surfaces are already available for Nobel Biocare’s On1 and Multi-unit Abutment, as © Nobel Biocare © Nobel Biocare Prof. Gabor Tepper. Dr Tristan Staas. well as for NobelActive and NobelParallel implants, and are backed by the latest evidence published in Clinical Implant Dentistry and Related Research. Nobel Biocare, Switzerland www.nobelbiocare.com/eao Hall 2, Booth C15[2] =>TDI0919_01-16.pdf news President of Portugal welcomes attendees at EAO 2019 Opening ceremony promises attendees an engaging learning atmosphere. At the opening ceremony, Dr Gil Alcoforado, chair of the 2019 EAO congress, officially announced that the 28th annual scientific meeting is underway. With attendees who have travelled from across Europe and beyond to participate, the congress is designed to impress and 130 speakers will be presenting a wide range of lectures, hands-on workshops and clinical video sessions. EAO 2019 is being held under the High Patronage of the President of the Portuguese Republic, Dr Marcelo Rebelo de Sousa. As part of this, a video of de Sousa was played during the opening ceremony in which he welcomed attendees and highlighted the country’s rich cultural heritage. “Portugal is not just a country with a long and important history, but one with a bright future as well,” de Sousa said. “I wish you not only an unforgettable stay in this country, but also hope that you will come back soon to get to know our culture better,” he added. © Brendan Day, DTI From left: Dr Susana Noronha and Dr Gil Alcoforado, co-chair and chair, respectively, of the 2019 EAO congress, at the opening ceremony. The President of EAO, Prof. Henning Schliephake, followed, also addressing the crowd via a pre-recorded video. The focus then turned to Alcoforado and Dr Susana Noronha, co-chair of the congress, who spoke about what they hoped to achieve under this year’s theme of “The bridge to the future”. Alcoforado thanked the members of the EAO congress and scientific committees, stating, “It is only through their tireless work that we can have such a large attendance from such a wide range of countries”. Over 4,000 attendees overall from more than 80 countries are expected to attend the congress, according to a press release from the EAO. “This is the first time the scientific meeting is taking place in Lisbon, making it an extra special occasion,” said Noronha. “I sincerely hope that this meeting exceeds your expectations and that you all have a fantastic congress.” “Using cell therapy for bone regeneration is promising” An interview with Prof. Kamal Mustafa, University of Bergen, by Franziska Beier, DTI. Prof. Kamal Mustafa from the Department of Clinical Dentistry at the University of Bergen in Norway is sponsoring and leading, together with Dr Cecilie Gjerde (University of Bergen) and Prof. Mariano Sanz (Complutense University of Madrid), a multicentre randomised controlled clinical trial (RCT) on stem cell bone building. This research is part of the European MAXIBONE project, which is investigating whether new jawbone prior to placement of dental implants can be grown with stem cell technology. At EAO 2019, Mustafa presented his research group’s work in a session that covered the topic of “New avenues in implant dentistry”. He shared insights into MAXIBONE with Dental Tribune International. Prof. Mustafa, you gave a lecture titled “Are stem cells the implants of the future?” On what did you focus during your presentation? The potential and value of stem cell-based therapies were explored in the early 1990s when therapeutically relevant tissue-supportive cells such as mesenchymal stem cells (MSCs) were applied for the regeneration of skeletal tissue. This new approach using cell therapy for bone regeneration is promising and could be used as an alternative for the classic gold standard treatment with bone grafts. The promising data from a recent clinical trial in 11 patients in Bergen, as part of the EU REBORNE project, has paved the way for improved, well-designed trials utilising stem cells for mandible augmentation and alveolar reconstruction. MAXIBONE began at the start of 2018 and will be completed in 2021. What is the current status of the project? MAXIBONE aims to create personalised bone regeneration by using 2 culture-expanded autologous bone marrow stem cells and biomaterials. The four-year project started with European funding of € 6 million. The large consortium is coordinated by Prof. Pierre Layrolle from the University of Nantes in France and me and gathers 12 partners from six European countries, including academic and research institutes, cell therapy units and companies, among them the global leader of dental implants. In the project, an RCT of 150 patients will compare the safety and efficacy of autologous cultured stem cells and calcium phosphate biomaterials with autologous bone grafting in alveolar bone augmentation prior to dental implants. In the previous European project, REBORNE, the clinical safety of this regenerative strategy was demonstrated in 11 patients. How does the process work exactly? Do the stem cells have to be autologous? Yes, autologous cells are harvested from bone marrow, expanded and cultured for two weeks in two cell manufacturing centres in Germany and France. Afterwards, they are delivered to the eight clinical centres in five European countries and implanted in patients in combination with biomaterials. The procedure has been reported in our recent publication by Gjerde et al. from 2018, which was part of the EU REBORNE project.1 Is this stem cell treatment less invasive than the standard bone transplant? The patients tolerated the treatment very well, as described and reported in the previously mentioned study. The data generated from the clinical trial demonstrated that bone 28 th EAO Annual Scientific Meeting © DTI Prof. Kamal Mustafa presenting at EAO 2019. marrow stem cells expanded successfully in the laboratory and, combined with synthetic bone substitute biomaterial in the patient to augment mandibular bone, induced significant new bone formation. The regenerated bone volume was adequate for dental implant installation. Healing was uneventful. The patients were satisfied with the aesthetic and functional outcomes. No side effects were observed. Could this method of bone replacement be used for other areas of the human body? Yes, a good example of using the method to repair long-bone defects has been demonstrated and reported in a study by Gómez-Barrena et al. from 2018.2 This interventional cli- nical trial was also part of the REBORNE project and performed to evaluate the safety and feasibility of autologous expanded MSCs from bone marrow associated with bioceramic (microporous biphasic calcium phosphate granules; MBCP+, Biomatlante) scaffolds in patients with longbone delayed unions and non-unions (after a minimum of three months from acute fracture). No severe adverse events related to the bone marrow MSCs were reported. The construct of stem cells combined with the biomaterial which was used in our maxillofacial clinical trial was surgically and successfully delivered to the non-unions, and 26 of 28 treated patients were found to be radiologically healed at one year after treatment. References: 1 Gjerde C, Mustafa K, Hellem S, Rojewski M, Gjengedal H, Yassin MA, Feng X, Skaale S, Berge T, Rosen A, Shi XQ, Ahmed AB, Gjertsen BT, Schrezenmeier H, Layrolle P. Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial. Stem Cell Res Ther. 2018 Aug 9;9(1):213. doi: 10.1186/ s13287-018-0951-9. 2 Gómez-Barrena E, Padilla-Eguiluz NG, Avendaño-Solá C, Payares-Herrera C, Velasco-Iglesias A, Torres F, Rosset P, Gebhard F, Baldini N, Rubio-Suarez JC, García-Rey E, Cordero-Ampuero J, Vaquero-Martin J, Chana F, Marco F, García-Coiradas J, Caba-Dessoux P, de la Cuadra P, Hernigou P, Flouzat-Lachaniette CH, Gouin F, Mainard D, Laffosse JM, Kalbitz M, Marzi I, Südkamp N, Stöckle U, Ciapetti G, Donati DM, Zagra L, Pazzaglia U, Zarattini G, Capanna R, Catani F. A multicentric, open-label, randomized, comparative clinical trial of two different doses of expanded hBM-MSCs plus biomaterial versus iliac crest autograft, for bone healing in nonunions after long bone fractures: study protocol. Stem Cells Int. 2018 Feb 22;2018:6025918. doi: 10.1155/2018/6025918.[3] =>TDI0919_01-16.pdf © DTI news “Implant therapy in the aesthetic zone is fraught with pitfalls” An interview with Dr Homa Zadeh, periodontist from Los Angeles, California, by Franziska Beier, DTI. With his presentation, Dr Homa Zadeh contributed to a session that considered the theme “Should we avoid implants in the aesthetic zone?” in the EAO 2019 scientific programme. He is a diplomate of the American Board of Periodontology and a past President of the Western Society of Periodontology. In a short interview with Dental Tribune International, Zadeh discussed the challenging aspects of placing implants in the aesthetic zone and the accompanying expectations of the patient. tion has to be based on both anatomical and prosthetic guidelines. By recognising all of these elements of risk, it is possible to manage them by proper decision-making and to maximise the predictability of the outcome. How do patients’ expectations of implants in the aesthetic zone vary from their expectations of implants elsewhere in the oral cavity? Any therapy in the anterior maxilla has very little leeway for error be- A packed audience listens to Dr Zadeh’s presentation. cause the outcome is directly visible by the patient and others. Implant therapy in the aesthetic zone is extra chal- lenging, because the outcome is a reflection of both the surgical and the prosthetic therapy performed. AD IT’S TIME FOR EFFICIENT 3D DIAGNOSIS © DTI Dr Homa Zadeh delivering his lecture in the auditorium of the Lisbon Congress Centre. You gave a lecture titled “Placing implants in the aesthetic zone”. On what topics did you focus during your presentation? My presentation focused on the decision-making process as the most important aspect of implant therapy in the aesthetic zone. There are dozens of decisions that have to be made that can affect the outcome. The bases on which those decisions are made were the focus of my presentation. What are the pros and cons of implants in the aesthetic zone, and what are the specific challenges of placing implants in the aesthetic zone? Implant therapy in the aesthetic zone is fraught with pitfalls, such as the variability of healing of tooth extraction sockets, as well as the variability of peri-implant mucosal changes. Implant installation is far more challenging in the anterior maxilla compared with other oral sites, whether implants are placed in extraction sockets or in healed sites. The combination of biological variability in outcomes, as well as technical challenges, can increase the likelihood of a negative outcome. However, rather than avoiding implants in the aesthetic zone altogether, it is important for clinicians to perform a thorough risk assessment in order to understand the risk factors and risk indicators that can influence the outcome. Important risk factors discussed included the alveolar bone phenotype of the extraction sockets (i.e. thin is less than 1 mm and thick greater than 1 mm) and the mucosal phenotype. Also, the 3D implant posi- Hall 10.2 3D diagnosis is more accessible than ever with a smart and compact solution - X-Mind® prime is manufactured by Dental X-ray Compagny and distributed by ACTEON. For dental professional use only. DE GOTZEN ® A Company of ACTEON® Group Via Roma 45 21057 Olgiate Olona VA ITALY Tel + 33 39 0331 376760 Fax + 39 0331 376763 E-mail: info@acteongroup.com www.acteongroup.com 28 th EAO Annual Scientific Meeting 3[4] =>TDI0919_01-16.pdf news “We usually think of rehabilitation as the responsibility of the clinician” An interview with Prof. Jocelyne Feine, McGill University, by Franziska Beier, DTI. As the percentage of older people in the population is growing, the number of elderly people depending on dental implants is increasing. Dental Tribune International spoke with Prof. Jocelyne Feine from the Faculty of Dentistry at McGill University in Montreal in Canada about the challenges of implant procedures in older people and how patients can contribute to the healing process. On 26 September, Feine spoke about the topic at the EAO 2019 congress. Prof. Feine, you gave a lecture on identifying the best treatment op- tions for older patients. On what topics did you focus during your presentation? I shared with the audience the factors that edentate older patients consider to be important regarding their prostheses. With that information, consideration of the most appropriate types of prostheses and number of implants was discussed. Why is implant treatment in elderly patients possibly more challenging? Elderly adults tend to have many chronic conditions and often take numerous medications that can interfere with the osseointegration pro- © DTI Prof. Jocelyne Feine speaking about challenges of placing dental implants in older patients. All pictures: © DTI Impressions of EAO 2019 4 28 th EAO Annual Scientific Meeting cess. They may also have physical restrictions that may make maintenance of oral hygiene difficult. How can elderly patients who have received dental implants contribute to the rehabilitation process? This is an interesting question, since we usually think of rehabilitation as the responsibility of the clinician. However, unless the patient is motivated and able to maintain his or her oral hygiene, treatment will fail. Thus, it is important for clinicians to assess their older patients’ motivation, as well as their ability to clean their mouths, the abutments, etc.[5] =>TDI0919_01-16.pdf news New hydrogel shows promise in dental and craniofacial tissue engineering Researchers from the University of California, Los Angeles School of Dentistry have developed a new hydrogel that shows high porosity and effectiveness in promoting tissue repair and regeneration. The study findings suggest that the next generation of hydrogel systems could greatly improve current biomaterial-based therapeutics to repair bone defects in the near future. Hydrogels are biomaterials that are made up of a 3D network of polymer chains. Owing to the network’s ability to absorb water and its structural similarities to living tissue, it can be used to deliver cells to defective areas to regenerate lost tissue. However, the small pore size of hydrogels limits the survival of the transplanted cells, their expansion and new tissue formation, making this less than ideal for regenerating tissue. Injectable combinations of living cells and bioactive molecules using hydrogels would be a preferred medical application to treat unhealthy or damaged areas of the body rather than more invasive surgery. Future research is planned to investigate how the physical properties of nanocomposite hydrogels affect the migration of cells and their function, as well as the formation of blood vessels. “Our nanocomposite hydrogel system will be useful for many applications, including therapeutic delivery, cell carriers, and dental and craniofacial tissue engineering,” concluded Lee. The study, titled “Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering”, was published in Nature Communications. AD © University of California, Los Angeles Microscopic image of regenerated bone. One material that has been of interest in the field of biomaterials is naturally occurring mineral clay. It has become an ideal additive to medical products and has no reported negative effects. It has been shown to be biocompatible and is readily available. Clay is structured in layers and its surface has a negative charge. This unique layered structure and charge were important to the research team, as the hydrogel they used had a positive charge. When the hydrogel was inserted into the clay layers through the process of intercalation chemistry, the end result was a clay-enhanced hydrogel with a much more porous structure, improving bone formation. Once the researchers had produced the clay-enhanced hydrogel, they used the process of photoinduction to turn their new biomaterial into a gel, which would make it easier for it to be injected into the mouse model. The mouse model had a nonhealing skull defect into which the researchers injected the clay-enhanced hydrogel. After six weeks, they found that the model showed significant bone healing through its own naturally occurring stem cell migration and growth. When asked by Dental Tribune International what the study results mean for dentistry and, specifically, for implantology, lead author Dr Min Lee, Professor of Biomaterials Science at the university answered: “This research will help us develop the next generation of hydrogel systems with high porosity for better bone repair and could greatly improve current bone graft materials.” The largest annual world Dental Meeting! Waiting for you in 2020! /ciosp _ciosp www.ciosp.com.br atendimento.congressista@apcdcentral.com.br 28 th EAO Annual Scientific Meeting 5[6] =>TDI0919_01-16.pdf news “Antibiotics are often overprescribed in an arbitrary manner and mostly unnecessarily in dentistry” An interview with Dr Ismael Khouly, New York University, by Franziska Beier, DTI. The use of antibiotics remains a controversial topic. A recent study1 investigated the necessity of antibiotics for the prevention of dental implant infections. Lead author Dr Is© Ismael Khouly mael Khouly, Associate Director of Periodontology and Implant Dentistry at Bluestone Center for Clinical Research at the New York University College of Dentistry in the US and his colleagues found that the prophylactic use of antibiotics has no influence on the prevalence of post-surgical dental implant complications in patients who are healthy overall. Khouly was so kind as to answer DTI’s questions on the topic. Dr Khouly, why did you focus on this topic for your study1? We decided to focus our systematic review on this topic because of the absence of current clinical guidelines for antibiotic prophylaxis in dental implant placement procedures, the misuse and overuse of antibiotics, and the risks associated with their prescription. While reviewing the medical literature, I noticed that existing guidelines on antibiotic prophylaxis in surgery, such as hip and knee arthroplasty, are often based on postoperative infection. Therefore, we decided to focus our systematic review on antibiotic prophylaxis to prevent surgical wound infection in dental implant surgeries rather than to prevent implant failure only. Furthermore, we investigated whether any specific antibiotic regimens with regard to antibiotic compound, dosage and dosing schedule were justified for specific evidence-based clinical guidelines. Our goal was to obtain more information and help clinicians to identify when to use antibiotics, responsibly, in dental implant placement procedures, to identify those clinical situations where antibiotics are recommended, as well as to choose the right antibiotic at the right dose and for the right duration. Would you say that antibiotics are generally prescribed too often? Unfortunately, antibiotics are often overprescribed in an arbitrary manner and mostly unnecessarily in dentistry, according to a recent study published in JAMA Network Open.2 This is important because around 10 % of the antibiotics used in the US are prescribed by dentists. Therefore, we must develop clinical guidelines for the rational use of antibiotics based on evidence and reduce the misuse of antibiotics. How can dentists be made aware of this situation? Every clinician involved in dental implant surgery procedures should take care not to overlook confounding variables while prescribing antibiotics in dental implant placement surgeries. Clinicians should understand that postoperative complications in implant dentistry, such as postoperative infection and implant failure, are most likely multifactorial and involve different risk factors which could be related to the clinician, the environment or the patient. Moreover, early implant failure may be caused by reasons other than postoperative infection, such as confounders from the surgical procedure as stated in a study by the International Team for Implantology Antibiotic Study Group.3 What would you recommend to dentists regarding antibiotic prescriptions for future implant surgeries? Bearing in mind the limitations of our systematic review, it seems that antibiotic prophylaxis may not prevent postoperative infections after dental implant placement procedures. However, and as stated in our study, “It is our recommendation that until such evidence becomes available, clinicians evaluate the benefits (or lack thereof) of antibiotic prophylaxis for each patient given medical history and surgical complexity and seriously consider results of the present paper for overall healthy patients, as well as risks associated with administration of antibiotics.”1 References: 1 Khouly I, Braun RS, Chambrone L. Antibiotic prophylaxis may not be indicated for prevention of dental implant infections in healthy patients. A systematic review and meta-analysis. Clin Oral Investig. 2019 Apr;23(4):1525–53. 2 Suda KJ, Calip GS, Zhou J, Rowan S, Gross AE, Hershow RC, Perez RI, McGregor JC, Evans CT. Assessment of the appropriateness of antibiotic prescriptions for infection prophylaxis before dental procedures, 2011 to 2015. JAMA Netw Open. 2019 May 31;2(5):e193909. doi: 10.1001/ jamanetworkopen.2019.3909. 3 Tan WC, Ong M, Han J, Mattheos N, Pjetursson BE, Tsai AY, Sanz I, Wong MC, Lang NP; ITI Antibiotic Study Group. Effect of systemic antibiotics on clinical and patient reported outcomes of implant therapy—a multicenter randomized controlled clinical trial. Clin Oral Implants Res. 2014 Feb;25(2):185–93. Eggshells may help heal teeth and bones Crushed or pulverised eggshells have many practical uses. They can be used as a natural calcium supplement, a coffee sweetener, a treatment for minor skin irritations and a nontoxic abrasive cleaner, or for garden compost and pest control. Recently, researchers also investigated the use of eggshells as material for bone grafts and for regenerating cartilage, teeth and tendons. The study, led by Dr Gulden Camci-Unal of the Department of Chemical Engineering at the University of Massachusetts Lowell, found an innovative use for powdered eggshells—which are composed mainly of calcium carbonate crystals—for engineering bone tissue that could lead to improved results for bone repair and healing. The researchers used microscopic eggshell particles to reinforce gelatin-based hydrogels, which then served as stable 3D scaffolds for growing osteoblasts. Camci-Unal said that this technique can be applied to treat and re- pair bones in patients who have suffered injuries due to aging or cancer and other diseases, as well as those injuries resulting from accidents or © Avelina/Shutterstock.com combat situations. The 3D structure can be used to grow not only bone for bone grafts but also cartilage, teeth and tendons, she added. “This is the first study that uses eggshell particles in a hydrogel matrix for bone repair,” noted CamciUnal. “We have already filed a patent application for it earlier this year. We are very excited about our results, and we anticipate a lot of impactful applications of our invention.” The study, titled “Eggshell particle-reinforced hydrogels for bone tissue engineering: An orthogonal approach”, was published in Biomaterials Science. Eggshells could play a role in bone grafting and other medical procedures. New research could help to tackle tooth loss and regeneration New research has shed light on the mechanism behind the formation of the periodontal ligament. The researchers found that the Notch signalling pathway, which is known to be activated in stem cells and cancer, is instrumental in periodontal ligament development. The findings will help scientists work towards regenerating the tissues that support teeth. The study was conducted by researchers from the universities of Plymouth and Geneva and focused on rat and mouse molar teeth. They found that lamin A, a cell nuclear protein, is a direct target of the Notch pathway. Lamin A is best known for its mutated form progerin, which causes the fatal “early ageing” disease called progeria syndrome. By 6 © University of Plymouth A recent study has examined regulation of periodontal ligament maturation at the molecular level. 28 th EAO Annual Scientific Meeting uncovering the involvement of lamin A in periodontal ligament formation, the scientists have gained a better insight into how molecules function during tissue regeneration and how the process could be affected during disease. “The periodontal ligament starts to properly hold the tooth in the jawbone when a tooth breaks out and becomes functional,” said co-author Dr Bing Hu, Associate Professor in Oral and Dental Health Research at the University of Plymouth’s Peninsula Dental School. “Understanding the mechanisms of how periodontal ligaments develop and the molecules that assist the tissue becoming mature is really important for our understanding of tissue regeneration and repair,” he continued. “The next steps are for us to see if and how the molecules we have identified in this study can be translated into a human-only model and, in turn, how they are affected in both healthy and diseased conditions.” “We believe that our findings are an important stepping stone to better dental treatments in situations involving the periodontal ligament, such as gum disease (periodontitis), tooth restoration by dental implants or orthodontic tooth movement,” said co-author Dr Balázs Dénes, a doctoral student at the University of Geneva. The study, titled “Notch coordinates periodontal ligament maturation through regulating lamin A”, was published in the Journal of Dental Research.[7] =>TDI0919_01-16.pdf [8] =>TDI0919_01-16.pdf floor plan Hall 2 Hall 1 E04 HOSPITALITY SUITE 1 HOSPITALITY SUITE 2 HOSPITALITY SUITE 3 O TO LL HAL 2 B60 A25 TO E-POSTERS ZONE C51 B62 F07 D27 A26 C49 B54 D28 F09 F11 G06 G08 G09 G07 D23 F18 F20 F19 F21 G10 G14 HOSPITALITY SUITE 5 H08 H06 G11 G17 - G19 G13 G21 G15 H12 D22 A22 D21 B48 F15 F13 HOSPITALITY SUITE 4 E05 - E07 D26 D25 B43 E01 EAO CHANNEL STUDIO H03 H09 H11 H13 ASSOCIATIONS CORNER D20 C35 A20 D19 B42 H15 D18 H17 C38 C33 A18 D16 B39 C31 B38 TO HALL 1 A15 D14 C30 B35 A11 TO HALL 3 TO FIRST FLOOR CONFERENCE ROOMS D10 C28 A10 A09 C27 B31 Hall 3 D07 D08 A08 TO HALL 1 B28 C25 K01 D04 B22 C20 D03 K02 A04 B17 D01 B18 A01 C12 C15 A02 I01 J02 J01–K03 K04 I03 J04 J03–K05 K06 ROOM 9 D02 ROOM 10 B14 Mezzanine Mezzanine C08 B07 B08 B10 C09 L04 C07 C06 B01 B02 B04 C05 L06 C03 TO E-POSTERS ZONE REGISTRATION I05 J06 TO REGISTRATION K12 ENTRANCE HALL 1 HALL 3 HALL 2 ENTRANCE This floor plan is a reproduction of the floor plan by the EAO. Changes or modifications may occur. 8 28 th EAO Annual Scientific Meeting L07 TO HANDS-ON SESSIONS ROOMS 11, 12, 13[9] =>TDI0919_01-16.pdf list of exhibitors Company Hall/Booth 3 Company Hall/Booth D 3SHAPE 2/B35 A DATUM DENTAL 1/G17–G19 Company Hall/Booth I-RES GROUP 2/B18 3/K12 JDENTALCARE ACE SURGICAL SUPPLY COMPANY 1/C07 DENTAL RATIO 2/C06 K ACTEON GROUP 1/H03 DENTIUM 2/B17 KLOCKNER IMPLANT SYSTEM DENTSPLY SIRONA 2/C27 L ALFA GATE 3/J01–K03 ALPHA BIOTECH 2/B14 DIO IMPLANT 2/C35 LIFENET HEALTH AMERICAN DENTAL SYSTEMS 1/H13 DR-KIM CO. 2/D02 M ANTHOGYR 2/D23 E ASEPTICO 2/C07 EMS ELECTRO MEDICAL SYSTEMS AVINENT IMPLANT SYSTEM 2/D10 B Q 2/B01 2/D04 2/B02 1/H17 R Company Hall/Booth SUNSTAR 2/A22 SURGIDENT CO. 3/L04 SWEDEN & MARTINA 3/I05 REGEDENT 2/A08 T RHEIN’83 1/G08 THOMMEN MEDICAL 2/B22 RUETSCHI TECHNOLOGY 1/H06 TI-OSS OCTABONE 2/D28 TRATE 2/B48 2/B38 S S.I.N. IMPLANTS 2/D27 TRI DENTAL IMPLANTS MALO CLINIC 2/A10 SAEYANG MICROTECH CO. 1/F21 TRUABUTMENT 1/F18 MAXILLARIS 3/K02 SANHIGIA THINK SURGICAL 2/B60 U EURONDA 2/A18 MECTRON 1/G15 SAUDE ORAL 3/J04 UBGEN 2/D01 EXAKTUS 2/B08 MEDENTIKA 2/HS2 SHINHUNG CO. 2/A04 USTOMED INSTRUMENTE 1/H09 2/A02 MEDENTIS MEDICAL 1/H11 SHINING 3D TECH CO. 2/D21 V SIC INVENT 2/D25 VERSAH B&B DENTAL IMPLANT COMPANY 2/D08 EXOCAD BEGO IMPLANT SYSTEMS 2/B43 F BEIJING YHJ SCIENCE Hall/Booth QUINTESSENCE PUBLISHING J DENTAL PRO Company MEDICAL INSTINCT 1/E05–E07 3/J02 FORESTADENT IMPLANTS 2/D18 DEUTSCHLAND 1/H08 SK BIOLAND CO. 2/A25 W 2/B04 MEDIDENT ITALIA 2/D26 SOUTHERN IMPLANTS 2/A26 W&H GROUP (W&H + OSSTELL) MEDIT 1/E01 SPEMD 3/K04 Y AND TRADE CO. 3/I03 FOTONA BIEN-AIR DENTAL 1/G14 G BIOHORIZONS CAMLOG 2/C25 GEISTLICH BIOMATERIALS 2/C31 MEGAGEN IMPLANT 2/A01 SPERO 3/K06 YUNYI MEDICAL DEVICE CO. BIOMEDICAL PRF-BRGF 3/I01 GLOBAL D 2/D07 MEISINGER 1/F07 SPPI 3/K01 Z BIOMEDICAL TISSUES 2/A09 H META 2/B07 S-TECH 2/D22 ZEST DENTAL SOLUTIONS BIONNOVATION BIOMEDICAL 2/D20 HU-FRIEDY MIS 2/C28 STOMA/STORZ AM MARK 1/G11 ZIBONE 1/G09 BIOTECH DENTAL 1/G10 I STRAUMANN 2/HS2 ZIMMER BIOMET 2/C30 BLUE M 1/G06 IBI SA SMARTBONE 2/D19 NEODENT 2/C49 BOTISS BIOMATERIALS 2/A15 IBS IMPLANT 2/C51 NEOSS 1/E04 IMPLACIL DE BORTOLI 1/F15 NIBEC CO. 2/B42 NOBEL BIOCARE SERVICES 2/C15 BREDENT GROUP 2/D14–D16 2/A20 N BRESMEDICAL 1/G13 IMPLANCE DENTAL BTI BIOTECHNOLOGY INSTITUTE 2/B39 IMPLANT SYSTEM 2/C08 NOVABONE PRODUCTS 1/F11 IMPLANTSWISS I-SYSTEM 2/C12 NSK 2/B10 NUCLEOSS 2/D03 NYU DENTISTRY 1/H12 C CARESTREAM DENTAL 2/C33 INTERNATIONAL TEAM CLARONAV 2/C09 FOR IMPLANTOLOGY CURAPROX 1/F19 INVIBIO BIOMATERIAL SOLUTIONS 2/B62 1/F20 about the publisher International Office/Headquarters Dental Tribune International GmbH Holbeinstraße 29, 04229 Leipzig, Germany Phone: +49 341 48474-302 Fax: +49 341 48474-173 E-mail: info@dental-tribune.com Internet: www.dental-tribune.com Production Executive Gernot Meyer Advertising Disposition Marius Mezger Production Matthias Abicht Publisher/Chief Executive Officer Torsten Oemus Chief Financial Officer Dan Wunderlich Director of Content Claudia Duschek Managing Editor Franziska Beier Assistant Editor Brendan Day Business Development & Marketing Manager Alyson Buchenau Sales & Production Support Puja Daya, Hajir Shubbar, Madleen Zoch today will appear at the 28th EAO Annual Scientific Meeting in Lisbon, 26 –28 September 2019. The newspaper and all articles and illustrations therein are protected by copyright. Any utilisation without prior consent from the editor or publisher is inadmissible and liable to prosecution. No responsibility shall be assumed for information published about associations, companies and commercial markets. General terms and conditions apply; legal venue is Leipzig, Germany. © 2019, Dental Tribune International GmbH. All rights reserved. Dental Tribune International makes every effort to report clinical information and manufacturer’s product news accurately, but cannot assume responsibility for the validity of product claims, or for typographical errors. The publishers also do not assume responsibility for product names, claims, or statements made by advertisers. Opinions expressed by authors are their own and may not reflect those of Dental Tribune International. O OMNIA 2/B31 ORTHOCELL 2/C05 OSSTELL 2/C20 OSSTEM IMPLANT 2/C38 OSTEOBIOL BY TECNOSS 2/B28 OSTEOGENICS BIOMEDICAL 1/F13 OSTEOLOGY FOUNDATION 2/A11 OXY IMPLANT 2/C03 P PENGUIN RFA 1/F09 PLANMECA 2/B54 PURGO BIOLOGICS 1/H15 2/C20 1/G21 3/J05–K05 AD is coming to PRAGUE 21–24 May 2020 Prague, Czech Republic www.ROOTS-SUMMIT.com 28 th EAO Annual Scientific Meeting 9[10] =>TDI0919_01-16.pdf industry PIONEERING TECHNOLOGY 2019: X-MIND PRIME 3D IS THE PERFECT PROFESSIONAL SOLUTION X-Mind prime is the latest addition to ACTEON’s CBCT digital imaging product line. It blends cutting-edge technology with ease of use in a compact design. With X-Mind prime 3D, high-tech is at your fingertips with tools for accurate diagnosis and complete treatment planning. It is a lightweight and compact system that can fit into any dental office. ACTEON is showcasing its new product at EAO 2019. X-Mind prime is a complete solution that combines 2D and 3D technologies. Using a single sensor, practitioners can quickly and easily switch between modes. With these features, X-Mind prime offers a wide range of possible examinations, 24 options for panoramic and 32 for CBCT, covering many clinical applications, including implantology, endodontics, and temporomandibular joint and sinus imaging. Practitioners can also scan 3D objects such as plaster models and silicone impressions, opening up new possibilities. Hence, all dental practices can now offer their patients 3D imaging and expand their clinical applications with this solution. These are just a few of the possibilities that X-Mind prime offers. Furthermore, when equipped with the ACTEON Imaging Suite precision software, which is compatible with both Windows and macOS operating systems, the unit provides advanced functionality. Intuitive image han- ensures an accurate, reliable and rapid treatment. X-Mind prime is a lightweight and compact system, and consequently, this equipment can fit into Delivered preassembled to the office and installed by a single specialist technician, the unit is up and running in under an hour, not interfering with the daily workload. dling and state-of-the-art tools simplify implant planning. In addition, customised reports improve communication and the unique solution facilitates diagnosis. For patients, this very small spaces. However, the ingenuity of X-Mind prime does not end there! With its intelligent wallmounted system, the unit adapts easily to all office space configurations. Using X-Mind prime provides true comfort to practitioners in their daily practice. The unit is also remarkably easy to use: the patient is positioned face to face with the prac- titioner while in operation, and the simplified control panel located under the chin support allows simple and accurate handling. Automatic chin support recognition, based on the type of operation selected, allows error-free patient positioning. This represents significant time-saving. Acquiring X-Mind prime is more than just buying a device. ACTEON believes the quality of its customer service is every bit as important as the quality of its products. The group provides personalised support based on each practitioner’s needs and specific situation. A pioneer in the manufacturing of innovative and less invasive dental imaging solutions, ACTEON is expanding its panoramic and CBCT product line with X-Mind prime. The device is an all-inone solution that integrates 2D and 3D imaging and combines all of the group’s high-tech expertise with its service quality. Attendees of EAO 2019 are invited to discover the new X-Mind prime 3D at ACTEON’s booth. ACTEON, France www.acteongroup.com Hall 1, Booth H03–H05 OSTEOBIOL GTO: A NEW STEP TOWARDS EXCELLENCE IN BIOMATERIALS At the beginning of this year, Tecnoss Dental, a leading biomaterials manufacturer based in Italy, launched a new bone substitute which combines innovative and advanced biotechnology, providing implantologists and periodontists with a grafting solution with improved surgical handling and predictable regenerative results. OsteoBiol GTO is endowed with all the characteristics of the ideal biomaterial for bone regeneration. This pioneering product is able to promote the three biological processes which guide bone regeneration: new bone apposition, neo-angiogenesis and progressive resorption of the scaffolding material, in order to promote adequate new bone formation. Tecnoss is showcasing GTO at this year’s EAO congress. GTO is a dual-phase biomaterial, because its granules contain both mineral and organic components. The preservation of collagen within the original xenogeneic cortical and cancellous bone matrix induces a physiological biological response by the patient’s bone tissue. Collagen has several significant advantages for bone regeneration, all scientifically well documented: it stimulates mesenchymal stem cell differentiation into osteoblasts, it is chemotactic, and it stimulates neo-angiogenesis and the absorption and subsequent release of growth factors. All these important biological benefits have determined the scientific rationale behind Tecnoss’s 20-yearlong research and development effort to produce a full range of collagenated dual-phase bone substitutes. The development of GTO is the last step of the process of continuous improvement by Tecnoss, starting with Apatos Cortical, a very osteoconductive but slowly resorbed scaffolding biomaterial. The first real breakthrough innovation has been Gen-Os, which is the precursor of all the dual-phase products. The outstanding OsteoBiol mp3 then followed as the first pre-hydrated bone substitute, packed in a ready-to-use syringe. In 2016, OsteoBiol TSV Gel, the thermosensitive viscosity resorbable gel which is used to create a sticky bone mix with Gen-Os, was launched. GTO combines all of the company’s experience and expertise in a unique product which is extremely versatile and achieves outstanding biological performance. GTO has an ideal viscosity, which means that it is very sticky and easily adaptable to the recipient site, making it a great option for treating various types of complex bone lesions. Its syringe formulation means that it is ready to use and is directly injectable into bone defects, making its handling easy and quick. GTO has been conceived as a universal biomaterial for use with OsteoBiol Evolution membranes or Lamina to protect the graft. Its stickiness and stability are useful properties for horizontal augmentation procedures (e.g. twowall defects, where the crest is resorbed) and for socket preservation cases with compromised buccal plates. During sinus lifting, GTO can be applied directly through the bony window, helping the stabilisation of implants in case of immediate placement. GTO can also be successfully used to treat peri-implant lesions, dehiscences and severe intra-bony defects. The product is already available in all EU countries and in other European markets where the OsteoBiol product line is distributed. For further information, visit www.osteobiol.com/contact. Tecnoss, Italy www.osteobiol.com Hall 2, Booth B28 10 28 th EAO Annual Scientific Meeting[11] =>TDI0919_01-16.pdf industry AESTHETICS REIMAGINED WITH INVERTA IMPLANT The INVERTA implant represents the latest breakthrough technology from Southern Implants and is designed for optimising aesthetics in maxillary anterior extraction socket sites. At EAO 2019, the company is showcasing its newest product. The INVERTA implant features a novel Body-Shift design that addresses challenges many clinicians face with immediate anterior implant procedures. The innovative design of the inverted coronal segment of the implant allows for a chamber for bone growth to be created, thereby enhancing the ability to obtain natural-looking aesthetics. The wider apical portion allows the implant to achieve the primary stability critical in immediate placement. INVERTA also incorporates proven features from Southern Implants’ other implant product lines, such as its SInergy Surface with decades of clinical research and high-strength Grade 4 pure titanium, which provides exceptional fatigue strength. The new implant is available with the popular deep conical internal and external hex connections. For treatment flexibility, INVERTA is available in a straight configuration and 12° Co-Axis, the latter offering built-in Subcrestal Angle Correction pected to be released throughout 2019 and beyond: • Chu SJ, Östman PO, Nicolopoulos C, Yuvanoglu P, Chow J, Nevins M, Tarnow DP. Prospective multicenter clinical cohort study of a novel macro hybrid implant in maxillary anterior postextraction sockets—1-year results. Int J Perio- dontics Restorative Dent. 2018; 38(Suppl):17–27. • Chu SJ, Tan-Chu JH, Levin BP, Sarnachiaro GO, Lyssova V, Tarnow DP. A paradigm change in macro implant concept: inverted body-shift design for extraction sockets in the esthetic zone. Compend Contin Educ Dent. 2019 Jul/Aug;40(7):444–52. • Nevins M, Chu SJ, Jang W, Kim DM. Evaluation of an innovative hybrid macrogeometry dental implant in immediate extraction sockets: a histomorphometric pilot study in foxhound dogs. Int J Periodontics Restorative Dent. 2019 Jan/Feb;39(1): 29–37. For more information during EAO 2019, please visit the company’s booth. Southern Implants, South Africa www.southernimplants.com Hall 2, Booth A26 AD PRAGODENT 2 7 th I N T E R N AT I O N A L D E N TA L FA I R 3–5 October 2019 NEWLY IN PARALLEL without using angled abutments, resulting in greater facial soft-tissue volume and providing ideal screwretained restorative options. Dr Pär-Olov Östman, a respected opinion leader who practises in Falun, Sweden, commented on the innovative implant design: “To be able to use INVERTA implants in aesthetically challenging cases gives me a predictable outcome with limited buccal recession and healthy soft tissue.” The following clinical research articles on INVERTA have been published and more articles are ex- LETŇANY PRAGUE 4–5 October 2019 pragodent.eu ORGANISER PLACE OF THE EVENT MAIN PROFESSIONAL PARTNER OFFICIAL CARS 28 th EAO Annual Scientific Meeting 11[12] =>TDI0919_01-16.pdf industry CLARONAV PRESENTS STATE-OF-THE-ART NAVIGATION FOR DAILY PRACTICE AT EAO 2019 Similarly to the way in which a GPS system guides a driver, Navident by ClaroNav guides clinicians by using the CBCT image as a map. It offers surgeons an easy-to-use, accurate, highly portable and affordable means of planning restorations and implant placements. With Navident 2, clinicians will no longer need to do a special extra scan. They can use the diagnostic scan already available for the patient. The stress of stent making is also gone because a stent is no longer required. Trace and Place (TaP) is a game-changing development for dynamic navigation. With TaP, the Navident workflow is streamlined, efficient, user-friendly and seamlessly integrated into the daily practice. “Trace and Place is a real tipping point for dynamic navigation guidance,” said user Dr George Mandelaris, a periodontist from Chicago in the US. “It has streamlined and simplified the workflow in both the diagnostic and surgical phases to allow state-of-the-art technology to be an everyday component of my surgical implant practice. I cannot imagine going back!” Implantology specialists who have used Navident 2.0 experienced negligible operator stress, improved time efficiency and an increase in patient acceptance. The Simplified Workflow with TaP (Trace Registration) ... which can be performed in a single appointment Plan Trace Place Plan restorative-driven implant placement on a laptop Register the CBCT scan to the patient by selecting 3-6 landmarks on the screen and tracing around those landmarks in the mouth with a tracer tool. Drill and place the implants under dynamic guidance The restoration and implant placement plan is created using the CT image data, optionally with added intraoral scans or any other surface data (STL files). The plan can be modified at any time, even during surgery. Navident is compatible with any implant size and type available on the market. The registration process that formerly involved making a thermoplastic stent, taking an additional CBCT scan with a significant opportunity for irrecoverable user error, has become an efficient, user friendly and easily repeatable 2 minute process. AD 12 28 th EAO Annual Scientific Meeting Following a brief drill or implant calibration, Navident dynamically presents the deviation between the actual/ planned position and orientation of the drill/ implant, guiding the surgeon to accurately implement the plan. accuracy offered by the new version, combined with the need for minimal tissue manipulation, is conducive to a shorter and better recovery process for patients, according to the company. Clinicians are invited to learn from masters and interact with their peers at ClaroNav’s booth at this year’s EAO meeting. ClaroNav, Canada www.claronav.com Hall 2, Booth C09[13] =>TDI0919_01-16.pdf PRINT EVENTS SERVICES EDUCATION DIGITAL Dental Tribune International The World's Dental Marketplace www.dental-tribune.com[14] =>TDI0919_01-16.pdf travel What’s on in Lisbon, 26 to 28 September Belém Tower • Where: Avenida Brasília • Opening hours: Tuesday–Sunday 10:00–18:30 This Lisbon landmark, built in the sixteenth century on the northern bank of the Tagus river, served as a fortress and ceremonial gateway to Lisbon. It was built during the height of the Portuguese Renaissance and is a prominent example of the Portuguese Manueline style but also incorporates hints of other architectural styles. Thus, both the interior and ex- terior of the tower offer much to explore and appreciate. Since 1983, the tower has been a UNESCO World Heritage Site, along with the Jerónimos Monastery. It is often portrayed as a symbol of Europe’s Age of Discovery and as a metonym for Portugal or Lisbon. © anyaivanova/Shutterstock.com Pastel de Belém • Where: Pastéis de Belém, Rua de Belém 84–92 • Opening hours: Daily 8:00–23:00 • Information: pasteisdebelem.pt/en/ AD The Pastéis de Belém bakery started to make its famous tarts of flaky pastry and custard in 1837 according to an ancient recipe from the Jerónimos Monastery. This secret recipe has remained unchanged ever since and is recreated every day, by hand, using only traditional methods. Besides the Pastel de Belém, the bakery offers other specialities. © Natalia Mylova/Shutterstock.com Banksy exhibition • When: 14 June to 27 October • Where: Cordoaria Nacional, Avenida da Ìndia • Opening hours: Monday–Friday and Sunday 10:00–19:00 | Saturday 10:00–20:00 • Information: www.banksyexhibition.pt/en/ Cordoaria Nacional—which is in close proximity to the Lisbon congress centre—is hosting the “Banksy: Genius or Vandal?” exhibition, the first big display in Portugal of the artist who revolutionised contemporary art and whose identity remains unknown. The immersive exhibition features more than 70 creations, lent by international private collectors and galleries, and includes original pieces, sculptures, installations, vid- 14 28 th EAO Annual Scientific Meeting[15] =>TDI0919_01-16.pdf travel and Technology), O’culto da Ajuda, the Museu Nacional de Arte Antiga and the Museu do Oriente. Entry is free. © SamuelThomas/Shutterstock.com © amnat30/Shutterstock.com Santa Casa Alfama 2019 festival • When: 27 and 28 September • Where: Different venues in Alfama • Information: www.visitlisboa.com/en/events/ festival-santa-casa-alfama-19 eos and photographs of the artist displayed in different themed areas. The experience begins with an audiovisual presentation, specifically created to welcome visitors to the exhibition, that reveals clues about the mysterious artist and highlights the most important pieces. Among the most recognised works of the exhibition is the original serigraph of the series Girl with Balloon. life to be lived and inviting an exploration of the tangible and intangible components of art and leisure. Street performances, concerts, traditional theatre and museums, contemporary cinema and digital art are just some of the art forms marking this event, which will take place at a number of venues, including the MAAT (Museum of Art, Architecture Santa Casa Alfama is a music festival that celebrates authentic and traditional Portuguese music. For two days, Lisbon’s eponymous district is taken over by Fado musicians and fans of all ages. Fado means “destiny” or “fate” and is a music genre that can be traced back to the 1820s in Lisbon, but probably has much earlier origins. In 2011, Fado was added to the representative list of Oral and Intangible Heritage of Humanity by UNESCO. © BLUR LIVE 1975/Shutterstock.com European Heritage Days 2019 • When: 27–29 September • Where: Different venues across the city • Information: www.visitlisboa.com/ en/events/european-heritagedays-19 The European Heritage Days 2019 will explore the theme of arts, heritage and leisure. The theme is intended to highlight the many facets of heritage linked to the arts, as a source of entertainment and leisure, allowing other dimensions of daily The seventh Santa Casa Alfama festival, with ten stages and more than 40 acts, invites music lovers to experience the traditional sounds of Portuguese music surrounded by the beautiful architecture of the oldest quarter in Lisbon. The performances take place in a wide variety of venues, from churches to museums, at outdoor venues and recreational associations, and provide visitors with a unique artistic range of music, worthy of appreciation. Useful information for the city of Lisbon • Time zone: UTC/GMT + 1 hour • Emergency numbers: Ambulance service/police: 112 • Currency: Euro • Tourist information: Rua do Arsenal 15 (Monday–Friday 9:30–19:00) • Foreign ministry: Portuguese Ministry of Foreign Affairs: www.portaldiplomatico.mne.gov.pt/en/ • Credit card acceptance: Credit cards like Mastercard and Visa are widely accepted throughout Portugal. However, it is advisable to carry some cash, as some restaurants or shops accept only cash or set a minimum purchase value of € 10 for credit card payments. Additional information for the EAO congress • Congress app: The congress registration fee includes the free download and use of the congress app. EAO attendees can use this app to view the programme, look at individual sessions and browse abstracts. At the end of the congress, participants can send themselves an individual visit report, including personal notes and bookmarks. Over the years, the app has become an essential tool for exclusive scientific content, promoting the congress’s aim of becoming paperless in the near future. AD REGISTER FOR FREE! DT Study Club – e-learning platform Join the largest educational network in dentistry! www.DTStudyClub.com Tribune Group GmbH is an ADA CERP Recognized Provider. ADA CERP is a service of the American Dental Association to assist dental professionals in identifying quality providers of continuing dental education. ADA CERP does not approve or endorse individual courses or instructors, nor does it imply acceptance of credit hours by boards of dentistry. Tribune Group GmbH designates this activity for one continuing education credit. 28 th EAO Annual Scientific Meeting 15[16] =>TDI0919_01-16.pdf Visit us at booth C15 Surface chemistry cells can’t resist. Introducing Xeal and TiUltra – two new breakthrough surfaces derived from our decades of applied anodization expertise. From abutment to implant apex, we have reimagined surface chemistry and topography to optimize tissue integration at every level. We’ve now entered the Mucointegration™ era. The new Xeal surface is now available for the On1™ Base and the Multi-unit Abutment. TiUltra is available on our best selling NobelActive® and NobelParallel™ CC implants.) 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